Figure 6.

Non-orthosteric Site 2: the TM1–TM7 cavity of β₁AR (A) and β₂AR (B). Side view of the cavity taken in the plane of the bilayer, depicting bound probe molecules and the key interacting tryptophan residue. Bound probe molecules are shown in ball-and-stick representation and colored by atom type. Tryptophan residue is shown in brown space-filling representation and labeled. Receptors are shown in blue molecular surface representation, with TM1 colored red and TM7 colored white. The experimental conformation of the receptor is shown.