Table 4. The results of the allelic association study by significant SNPs.
SNP | Position in mtDNA (bp) | Allele frequency | P-value | OR | CI | Function | Haplogroup | ||
---|---|---|---|---|---|---|---|---|---|
AD | CTRL | L95 | U95 | ||||||
MitoA11467G | 11467 | 0.28 | 0.14 | 0.003 | 2.22 | 1.3 | 3.78 | NADH dehydroenase (ND4) | U and Uk |
MitoA12308G | 12308 | 0.3 | 0.17 | 0.006 | 2.03 | 1.23 | 3.34 | tRNA for leucine (CUN) | U and Uk |
MitoG12372A | 12372 | 0.3 | 0.18 | 0.006 | 1.99 | 1.21 | 3.27 | NADH dehydroenase (ND5) | U and Uk |
MitoC9698T | 9698 | 0.17 | 0.08 | 0.021 | 2.26 | 1.16 | 4.41 | Cytochrome C oxidase (COIII) | U8 (Uk) |
MitoC16270T | 16270 | 0.09 | 0.03 | 0.048 | 2.52 | 1 | 6.36 | non-coding region | Not specific |