Table 1.
Incidence of acute myeloid leukaemia after low-dose radioiodine treatment for thyroid disorders
| Case | Age years | Dose of 131I (mCi) | Time in months from 131I to AML onset | Type of myeloid leukaemia | Karyo-type | Reference |
|---|---|---|---|---|---|---|
| 1 | NA | 100 | 12 | Acute granulocytic | NA | Beierwaltes, 1981 |
| 2 | 19 | 230 | 24 | Acute myeloblastic | NA | Siemsen, 1970 |
| 3 | 28 | 300 | 14 | AML M4 | NA | Bitton, 1993 |
| 4 | 34 | 150 | 24 | AML M2 | NA | Roldan Schilling, 1998 |
| 5 | 43 | 150 | 60 | AML M3 | NA | Roldan Schilling, 1998 |
| 6 | 48 | 23 | 14 | AML M2 | Trisomy 8 | Laurenti, 1998 |
| 7 | 47 | 118 | 14 | AML M3 | t(15,17) | Grudeva-Popova, 2007 |
| 8 | 55 | 90 | 144 | AML M4 | Iso 7q | Focosi, 2007 |
| 9 | 51 | 22.1 | 27 | AML M3 | NA | Kolade, 2005 |
| 10 | 48 | 100 | 17 | AML M2 | Trisomy 3 | Our case, 2007 |
mCi = Millicurie; Iso = isochromosome; NA = not available.