Table III.

Summary of Studies in Sepsis Populations

Study	N	GIK Formulation	Duration of Infusion	Mortality	% Change MAP Post-GIK	% Change Cardiac Function Post-GIK	Adverse Events
Clowes 1974	10	1 g/kg glucose; 1.5 U/kg insulin; 10 mEq KCL	10 min	40%	30% increase	187% increase (CO)	None reported
Weisul 1975	6	1 g/kg glucose; 1.5 U/kg insulin; 15 mEq KCL	10 min	67%	30% increase	244% increase (CI)	None reported
Vincent 1981	6	75 g glucose; 100 U insulin; 15 mEq KCL	40 min	NR	NR	27% increase (CO)	None reported
Bronsveld 1985	15	1 g/kg 50% glucose; 1.5 U/kg insulin; 10 mmol KCL	20 min	67%	5% increase	12.5% increase (CI)	None reported
Mauritz 1986	14	1 g/kg 70% glucose; 1.5 U/kg insulin; 10 mmol KCL	15 min	86%	61% increase	50% increase (CI)	None reported
Hamdulay 2006	2	30% glucose; 50 U insulin; 80 mmol KCL	18–72 h	100%	9% increase	88% increase (CO)	None reported

CI, cardiac index; CO, cardiac output; GIK, glucose–insulin–potassium; KCL, potassium chloride; MAP, mean arterial pressure; N, number of patients in study; NR, not reported.