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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: JAMA. 2010 Feb 24;303(8):739–746. doi: 10.1001/jama.2010.158

Table 2.

Systemic Inflammatory Response Criteria and Dysfunctional Organ Systems

Variable No. (%) of Patients
Lactate Clearance Group (n = 150) ScvO2 Group (n = 150)
SIRS criteria
 Abnormal white blood cell count

117 (78)

104 (69)
 Elevated heart rate 100 (67) 108 (72)
 Elevated respiratory rate 96 (64) 89 (59)
 Abnormal body temperature 61 (41) 64 (43)
Organ dysfunction
 Respiratory

85 (57)

86 (57)
 Liver 43 (29) 43 (29)
 Neurological 47 (31) 58 (39)
 Coagulation 51 (34) 39 (26)
 Cardiovascular 132 (88) 128 (85)
 Renal 110 (73) 109 (73)

Abbreviations: ScvO2, central venous oxygen saturation; SIRS, systemic inflammatory response syndrome.