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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: JAMA. 2010 Feb 24;303(8):739–746. doi: 10.1001/jama.2010.158

Table 4.

Administered Treatments and Resuscitation Goals

Intervention, h No. (%) of Patients P Valuea
Lactate Clearance Group (n = 150) ScvO2 Group (n = 150)
Crystalloid volume, mean (SD), L
 0-<6
4.5 (2.36)
4.3 (2.21)
.55
 6–72 12.4 (6.15) 11.8 (6.41) .44
Vasopressor administration
 0-<6
108 (72)
113 (75)
.60
 6–72 100 (67) 108 (72) .45
Dobutamine administration
 0-<6
5 (3)
8 (5)
.57
 6–72 10 (7) 13 (9) .66
PRBC transfusion
 0-<6
11 (7)
5 (3)
.20
 6–72 35 (23) 31 (21) .78
Mechanical ventilation
 0-<6
40 (27)
39 (26)
.99
 6–72 69 (46) 75 (50) .56
Activated protein C
 0-<6
0
0
 6–72 3 (2) 2 (1) .68
Parenteral corticosteroids
 0-<6
18 (12)
26 (17)
.25
 6–72 59 (39) 51 (34) .40

Abbreviations: PRBC, packed red blood cell; ScvO2, central venous oxygen saturation.

a

Continuous variables are compared using unpaired t test; categorical variables, using χ2 test except activated protein C which was analyzed using Fisher exact test.