Table 5.
Variable | Lactate Clearance Group (n = 150) | ScvO2 Group (n = 150) | Proportion Difference (95% Confidence Interval) | P Valueb |
---|---|---|---|---|
In-hospital mortality, No. (%)a Intent to treat |
25 (17) |
34 (23) |
6 (−3 to 15) |
|
Per protocol | 25 (17) | 33 (22) | 5 (−3 to 14) | |
Length of stay, mean (SD), d ICU |
5.9 (8.46) |
5.6 (7.39) |
.75 |
|
Hospital | 11.4 (10.89) | 12.1 (11.68) | .60 | |
Hospital complications Ventilator-free days, mean (SD) |
9.3 (10.31) |
9.9 (11.09) |
.67 |
|
Multiple organ failure, No. (%) | 37 (25) | 33 (22) | .68 | |
Care withdrawn, No. (%) | 14 (9) | 23 (15) | .15 |
Abbreviations: ICU, intensive care unit; ScvO2, central venous oxygen saturation.
Primary study end point.
Continuous data are compared using an unpaired t test; categorical variables, using the χ2 test.