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. 2010 Sep;51(9):2629–2641. doi: 10.1194/jlr.M005132

Fig. 6.

Fig. 6.

Gibbs triangle showing DRM (solid) and DSM (open) compositions for all the systems tested in this work: DRM-like (▪), DSM-like (□), different raft-containing membranes (i) in the absence of AChR (•, ○), (ii) in the presence of γM4 peptide (1:250 ▴, △), and (iii) in the presence of different AChR:lipid molar ratios (1:400, ▾, ▽; and 1:130, ♦, ⋄). The DRM and DSM lipid compositions proposed in the work of Schroeder et al. (50) (◂, ◃) and McIntosh et al. (51) (▸, ▹) are indicated. Also shown are the lines that divide the phase diagram in the different pure phases (solid, s; liquid-ordered, lo; and liquid disordered, ld) and the different coexistence regions at 22°C (s + lo; ld + lo + s; ld + s; and ld + lo) proposed by Pokorny et al. (70). AChR, nicotinic acetylcholine receptor; BSM, brain sphingomyelin; Chol, cholesterol; DRM, detergent-resistant membrane; DSM, detergent-soluble membrane; POPC, palmitoyloleylphosphatydilcholine.