FIG. 4.
Transduction and circularization with ssAAV and scAAV in ATR-deficient cells. Cells containing doxycycline-inducible wt (wt ATR) or dominant-negative (ATRKD) ATR transgenes were infected with the four reporter vectors used for Fig. 1 at an MOI of 0.5 for 2 h. Doxycycline (DOX) treatment was initiated 48 h before infection and maintained through the experiment. GFP expression was quantified by flow cytometry at 24 h postinfection. The indicated (*) differences between wt and ATR-deficient cells were significant (P < 0.0010). Error bars indicate standard deviations.