TABLE 1.
Virus production by adenovirus-infected B-cell linesa
| Cell line | No. of days postinfection | Virus production |
||
|---|---|---|---|---|
| No. of genomes/cell | No. of PFU/cell | No. of genomes/PFU | ||
| BJAB | 1 | 10 | 32 | 5 |
| 14 | 9,800 | 6 | 1,600 | |
| 21 | 4,400 | 6 | 700 | |
| 35 | 3,600 | 5 | 700 | |
| 42 | 2,600 | 2 | 1,300 | |
| 49 | 1,900 | 2 | 1,000 | |
| Ramos | 24 | 5,400 | 1 | 5,400 |
| 31 | 2,600 | 2 | 1,300 | |
| 45 | 2,200 | 2 | 1,100 | |
| 59 | 1,100 | 2 | 550 | |
| 73 | 4,100 | 1 | 4,100 | |
a
Cells were infected with Ad5dl309 at 100 PFU/cell. Infected cells were collected weekly. Plaque assays were performed on permissive A549 cells. Viral DNA was quantified by real-time PCR.