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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Cell Host Microbe. 2010 May 20;7(5):354–361. doi: 10.1016/j.chom.2010.04.007

Fig. 6. PKR promotes IFN-β protein production in response to infection with EMCV in vivo.

Fig. 6

IFN-β protein was measured in the serum of mice that had been infected with EMCV 20 hours earlier. (A) Wild-type (129 Sv) and PKR−/− mice (mixed 129 Sv/C57BL/6 background), p<0.006 (n=10). (B) Wild-type (C57BL/6) and PKR−/− mice (C57BL/6 background), p<0.008 (n=5). (C) MyD88−/− and MyD88−/− × PKR−/− mice, p<0.03 (n=4). (A–C) Dots represent individual mice, error bars are mean ± SD. Data in each panel are representative of two independent experiments with similar results. Paired data were analysed using a two-tailed Mann-Whitney test.