Table 1.
Clinical, histologic, and microbiologic characteristics of necropsied mice
| Age (mo) | Sex | Strain | Lesion | Tissues or organs involved | Granuloma? | Microbiology |
| 4 | M | B6p47phox[KO]HLL | Abscess | Head, neck, brain, and lung | Yes | S. xylosus |
| 5 | M | B6p47phox[KO]HLL | Abscess | Cervical lymph nodes, mandible | No | S. xylosus, E. coli,Micrococcus sp. |
| 7 | M | B6p47phox[KO]HLL | Abscess | Lung | No | S. xylosus |
| 9 | M | B6p47phox[KO]HLL | Abscess | Cervical lymph nodes, maxilla, lung | No | S. xylosus |
| 10 | M | B6p47phox[KO]HLL | Abscess | Lymph nodes, lung, limb skin and bone | No | S. xylosus |
| 12 | M | B6p47phox[KO]HLL | Abscess | Lung | No | S. xylosus |
| 16 | M | B6p47phox[KO]HLL | Abscess | Cervical lymph nodes, mandible | No | S. xylosus |
| 6 | F | B6p47phox[KO]HLL | Abscess | Skin, lung, brain | No | S. xylosus |
| 7 | F | B6p47phox[KO]HLL | Abscess | Cervical lymph nodes, maxilla, lung | No | S. xylosus |
| 7 | F | B6p47phox[KO]HLL | Dermatitis | Muzzle skin | Yes | S. xylosus |
| 7 | F | B6p47phox[KO]HLL | Dermatitis | Muzzle skin | Yes | S. xylosus |
| 2 | M | B6.129S6-Cybbtm1Din/J | Abscess | Head, brain, lung | Yes | S. xylosus, Enterococcus fecalis,Micrococcus sp., Bacillus sp. |
| 8 | M | B6.129S6-Cybbtm1Din/J | Abscess | Muzzle, skull | Yes | S. xylosus |
| 12 | M | B6.129S6-Cybbtm1Din/J | Abscess | Maxilla, lymph node, lung | No | S. xylosus |
| 12 | M | B6.129S6-Cybbtm1Din/J | Abscess | Maxilla, lymph node, lung, brain | No | S. xylosus |
| 8 | F | B6.129S6-Cybbtm1Din/J | Abscess | Skull, leg, lymph node | Yes | S. xylosus |
| 19 | F | B6.129S6-Cybbtm1Din/J | Abscess | Neck, lung | Yes | S. xylosus |
| 7 | M | AKR/J-Lvif | Conjunctivitis, blepharitis, dermatitis | Eyelid and conjunctiva, perineum | No | S. xylosus,Corynebacterium pseudotuberculosis, Lactobacillus sp., Pasteurella sp. |
| 9 | M | AKR/J-Lvif | Conjunctivitis, blepharitis | Eyelid and conjunctiva | No | S. xylosus,S. epidermidis |
| 9 | M | AKR/J-Lvif | Conjunctivitis, blepharitis | Eyelid and conjunctiva | No | S. xylosus, S. sciuri,Enterococcus sp., Candida sp., Stenotrophomonas maltophilia |
| 12 | M | AKR/J-Lvif | Conjunctivitis, blepharitis | Eyelid and conjunctiva | No | S. xylosus |
| 12 | M | AKR/J-Lvif | Conjunctivitis, blepharitis | Eyelid and conjunctiva | No | S. xylosus |
| 6 | F | AKR/J-Lvif | Skin/mucosal ulcers | Perineum, anus, rectum, vagina | No | S. xylosus, E. coli,Enterococcus sp. |
| 21 | M | B6.129S2-Ncf1tm1shlN14 | Abscess | Lung, pelvic muscles | No | S. xylosus |
| 12 | F | B6.129S2-Ncf1tm1shlN14 | Abscess | Leg muscles and bone | No | S. xylosus |
| 19 | F | B6.129S2-Ncf1tm1shlN14 | Dermatitis | Skin | No | S. xylosus |
| 19 | M | B6;129-Adora2atm1Dyj/J | Conjunctivitis, blepharitis | Eyelid and conjunctiva | No | S. xylosus |
| 19 | M | B6;129-Adora2atm1Dyj/J | Conjunctivitis, blepharitis | Eyelid and conjunctiva | No | S. xylosus, Micrococcus sp. |
| 2 | M | BALB/c | Conjunctivitis, dermatitis | Eye conjunctiva, skin | No | S. xylosus, Aerococcus sp., Pasteurella sp. |
| 7 | M | BALB/c | Dermatitis | Skin | Yes | S. xylosus |
| 12 | M | NOD.Cg-Prkdcscid Il2rgtm1Sug/JicTac | Adenitis | Preputial gland | No | S. xylosus, Raoultella ornithinolytica |
| 1 | M | C57BL/6Ncr-[KO]P47phoxN14 | Abscess | Maxilla, lung | Yes | S. xylosus |
| 24 | M | NFS/N-Xpr1Sxv Rmcf2+ | Vesiculitis | Seminal vesicle, urethra | No | S. xylosus, E. coli,Enterobacter sp. |
| 1 | F | C57BL/6NTac-[KO]P50NF-kB-[KO]P52NF-kB | Dermatitis | Skin | No | S. xylosus, S. sciuri |
| 7 | F | C57BL/6J-[KO]RAG1 N10 | Dermatitis | Skin | No | S. xylosus |
| 7 | M | AKR/J-Xpr1Sxv | Conjunctivitis, blepharitis | Eyelid and conjunctiva | No | S. xylosus |
| 1 | F | C57BL/6NTac-[KO]FPR | Blepharitis, keratitis | Eyelid, cornea | No | S. xylosus |
M, male; F,female