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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Cancer Res. 2010 Jun 22;70(13):5628–5638. doi: 10.1158/0008-5472.CAN-10-0595

Figure 2.

Figure 2

RAGEv1 inhibits RAGE-ligand induced changes in tumorigenic gene expression. (A-B) Relative gene expression of PDGFB and TNF were determined by QPCR on mock and RAGEv1 expressing cells, stimulated with RAGE-ligand (s100B), gene expression normalized to GAPDH levels. (C-D) Western blot analysis of cyclin D1 and Apaf1 performed on cell lysates from mock and RAGEv1 cells, stimulated with RAGE-ligand (s100B), normalized to GAPDH levels. Data are means ± SEM from three independent experiments and significant differences (P ≤ 0.05) indicated by an asterisk.