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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Cancer Res. 2010 Jun 22;70(13):5628–5638. doi: 10.1158/0008-5472.CAN-10-0595

Figure 6.

Figure 6

RAGEv1 inhibits tumorigenesis in vitro and in vivo. (E) RAGEv1 inhibits tumorigenic growth in vitro. Soft agar assay were performed with mock and RAGEv1 transfected cells cultured for 14 days and stained with crystal violet. (A) Athymic nude mice were injected with either mock or RAGEv1 expressing tumor cells and tumor growth measured after 31 days. (B) Protein was extracted ex vivo from mock (Ma-c) and RAGEv1 (RAGEv1a-c) tumors and subjected to western blot for phospho and total levels of SAPK/JNK. Significant differences (P ≤ 0.05) between groups are indicated by an asterisk.