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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: J Hypertens. 2010 Apr;28(4):748–755. doi: 10.1097/HJH.0b013e3283355672

Table 2.

Significance values for associations of individual SNPs with BP response to potassium supplementation using population based (GEE) and family based (QTDT) statistical methods.

GEE QTDT
Gene SNP SBP DBP MAP SBP DBP MAP
EDN1 rs1476046 0.191 0.042* 0.037* 0.909 0.144 0.178
EDN1 rs1630736 0.037* 0.390 0.136 0.447 0.357 0.304
EDN1 rs1800541 0.030* 0.013* 0.010* 0.159 0.006** 0.010*
EDN1 rs1800543 0.235 0.092 0.058 0.598 0.190 0.161
EDN1 rs2859338 0.840 0.656 0.824 0.708 0.771 0.648
EDN1 rs3087459 0.064 0.029* 0.025* 0.161 0.021* 0.023*
EDN1 rs5370 0.217 0.093 0.056 0.692 0.225 0.212
NOS3 rs10277237 0.879 0.666 0.451 0.897 0.830 0.959
NOS3 rs1800781 0.859 0.178 0.275 0.544 0.785 0.957
NOS3 rs3918227 0.681 0.909 0.809 0.586 0.992 0.808
NOS3 rs743507 0.829 0.113 0.196 0.774 0.191 0.382
NOS3 rs7830 0.165 0.898 0.275 0.391 0.171 0.501
SELE rs3917406 0.402 0.500 0.408 0.898 0.665 0.836
SELE rs3917419 0.823 0.799 0.883 0.530 0.572 0.416
SELE rs4786 0.359 0.305 0.239 0.756 0.946 0.995
SELE rs5368 0.500 0.567 0.515 0.781 0.900 0.945
SELE rs932307 0.178 0.088 0.071 0.805 0.554 0.604

SBP: Systolic blood pressure, DBP: diastolic blood pressure, MAP: Mean arterial pressure, GEE: Generalized Estimation Equation.

*

P<0.05

**

P<0.01