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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Am J Ophthalmol. 2010 May;149(5):713–727. doi: 10.1016/j.ajo.2009.12.011

Table 5.

Four-year Incidence of Monocular Blindness in the Los Angeles Latino Eye Study

Age at baseline
(years)
Incidence in 1st Eye Incidence in 2nd Eye Incidence in Either Eye

N n % (CI) N n % (CI) N n % (CI)
United States Criterion*

     40–49 1733 4 0.2 (0.0, 0.5) 22 0 NA 1755 4 0.2 (0.0, 0.5)
     50–59 1431 10 0.7 (0.3, 1.1) 22 4 18.7 (2.1, 34.3) 1453 14 1.0 (0.5, 1.5)
     60–69 911 21 2.3 (1.3, 3.3) 24 0 NA 935 21 2.2 (1.3, 3.2)
     70–79 383 15 3.9 (2.0, 5.9) 16 2 12.5 (0.0, 28.7) 399 17 4.3 (2.3, 6.2)
     80+ 71 4 5.6 (0.3, 11.0) 8 1 12.5 (0.0, 35.4) 79 5 6.3 (1.0, 11.7)
P < 0.001 P = 0.418 P < 0.001
  Crude Overall 4529 54 1.2 (0.9, 1.5) 92 7 7.6 (2.2, 13.0) 4621 61 1.3 (1.0, 1.6)

Age-standardized# 1.2 (0.9, 1.5) 7.0 (1.8, 12.2) 1.3 (1.0, 1.7)

World Health Organization Criterion

     40–49 1745 8 0.5 (0.1, 0.8) 11 0 NA 1756 8 0.5 (0.1, 0.8)
     50–59 1437 6 0.4 (0.1, 0.8) 16 3 18.8 (0.0, 37.9) 1453 9 0.6 (0.2, 1.0)
     60–69 919 14 1.5 (0.7, 2.3) 17 0 NA 936 14 1.5 (0.7, 2.3)
     70–79 391 9 2.3 (0.8, 3.8) 11 1 9.1 (0.0, 26.1) 402 10 2.5 (1.0, 4.0)
     80+ 76 5 6.6 (1.0, 12.2) 5 1 20.0 (0.0, 55.1) 81 6 7.4 (1.7, 13.1)
P < 0.001 P = 0.581 P < 0.001
  Crude Overall 4568 42 0.9 (0.6, 1.2) 60 5 8.3 (1.3, 15.3) 4628 47 1.0 (0.7, 1.3)
Age-standardized# 0.9 (0.6, 1.2) 7.0 (0.9, 13.1) 1.0 (0.7, 1.3)

N=number at risk at baseline; n= incident cases; % (CI)= prevalence and 95 percent confidence interval; P = Test of trend.

*

US Modified Criterion. Incidence of Monocular Blindness (1st or 2nd eye): Persons with Baseline BCVA better than 20/200 in the 1st or 2nd eye and follow-up BCVA 20/200 or worse (including 20/200) in the 1st or 2nd eye.

W.H.O. modified Criterion. Incidence of Monocular Blindness (1st or 2nd eye): Persons with Baseline BCVA 20/400 or better in the 1st or 2nd eye and follow-up BCVA worse than 20/400 (not including 20/400) in the 1st or 2nd eye.

This column combines the incidence in the first eye and incidence in the second eye.

NA: No incident cases.

#

Age-standardized to the LALES population.