Table 5.
Four-year Incidence of Monocular Blindness in the Los Angeles Latino Eye Study
| Age at baseline (years) |
Incidence in 1st Eye | Incidence in 2nd Eye | Incidence in Either Eye ∥ | ||||||
|---|---|---|---|---|---|---|---|---|---|
| N | n | % (CI) | N | n | % (CI) | N | n | % (CI) | |
| United States Criterion* | |||||||||
| 40–49 | 1733 | 4 | 0.2 (0.0, 0.5) | 22 | 0 | NA | 1755 | 4 | 0.2 (0.0, 0.5) |
| 50–59 | 1431 | 10 | 0.7 (0.3, 1.1) | 22 | 4 | 18.7 (2.1, 34.3) | 1453 | 14 | 1.0 (0.5, 1.5) |
| 60–69 | 911 | 21 | 2.3 (1.3, 3.3) | 24 | 0 | NA | 935 | 21 | 2.2 (1.3, 3.2) |
| 70–79 | 383 | 15 | 3.9 (2.0, 5.9) | 16 | 2 | 12.5 (0.0, 28.7) | 399 | 17 | 4.3 (2.3, 6.2) |
| 80+ | 71 | 4 | 5.6 (0.3, 11.0) | 8 | 1 | 12.5 (0.0, 35.4) | 79 | 5 | 6.3 (1.0, 11.7) |
| P < 0.001 | P = 0.418 | P < 0.001 | |||||||
| Crude Overall | 4529 | 54 | 1.2 (0.9, 1.5) | 92 | 7 | 7.6 (2.2, 13.0) | 4621 | 61 | 1.3 (1.0, 1.6) |
| Age-standardized# | 1.2 (0.9, 1.5) | 7.0 (1.8, 12.2) | 1.3 (1.0, 1.7) | ||||||
| World Health Organization Criterion† | |||||||||
| 40–49 | 1745 | 8 | 0.5 (0.1, 0.8) | 11 | 0 | NA | 1756 | 8 | 0.5 (0.1, 0.8) |
| 50–59 | 1437 | 6 | 0.4 (0.1, 0.8) | 16 | 3 | 18.8 (0.0, 37.9) | 1453 | 9 | 0.6 (0.2, 1.0) |
| 60–69 | 919 | 14 | 1.5 (0.7, 2.3) | 17 | 0 | NA | 936 | 14 | 1.5 (0.7, 2.3) |
| 70–79 | 391 | 9 | 2.3 (0.8, 3.8) | 11 | 1 | 9.1 (0.0, 26.1) | 402 | 10 | 2.5 (1.0, 4.0) |
| 80+ | 76 | 5 | 6.6 (1.0, 12.2) | 5 | 1 | 20.0 (0.0, 55.1) | 81 | 6 | 7.4 (1.7, 13.1) |
| P < 0.001 | P = 0.581 | P < 0.001 | |||||||
| Crude Overall | 4568 | 42 | 0.9 (0.6, 1.2) | 60 | 5 | 8.3 (1.3, 15.3) | 4628 | 47 | 1.0 (0.7, 1.3) |
| Age-standardized# | 0.9 (0.6, 1.2) | 7.0 (0.9, 13.1) | 1.0 (0.7, 1.3) | ||||||
N=number at risk at baseline; n= incident cases; % (CI)= prevalence and 95 percent confidence interval; P = Test of trend.
US Modified Criterion. Incidence of Monocular Blindness (1st or 2nd eye): Persons with Baseline BCVA better than 20/200 in the 1st or 2nd eye and follow-up BCVA 20/200 or worse (including 20/200) in the 1st or 2nd eye.
W.H.O. modified Criterion. Incidence of Monocular Blindness (1st or 2nd eye): Persons with Baseline BCVA 20/400 or better in the 1st or 2nd eye and follow-up BCVA worse than 20/400 (not including 20/400) in the 1st or 2nd eye.
This column combines the incidence in the first eye and incidence in the second eye.
NA: No incident cases.
Age-standardized to the LALES population.