. Author manuscript; available in PMC: 2011 May 1.

Published in final edited form as: Cancer. 2010 May 1;116(9):2180–2187. doi: 10.1002/cncr.25028

Table 3.

Risk Factors by Response Group

	CR/nPR N (%)	Not CR/nPR N (%)	P value	TFS Estimate months (95% CI)	Log rank p value
Age
< 70	13 (54%)	11 (46%)	0.05	15.8 (11.2-23.7)	0.13
≥ 70	1 (11%)	8 (89%)		14.8 (6.5-18.9)
CD38
Negative (≤ 30)	10 (48%)	11 (52%)	0.49	15.8 (11.2-23.7)	0.43
Positive (>30)	4 (33%)	8 (67%)		20.6 (5.0- 20.6)
Zap 70 ^*
Negative (≤ 20)	5 (31%)	11 (69%)	0.47	15.7 (13.6-15.9)	0.26
Positive (>20)	8 (50%)	8 (50%)		20.6 (10.8-25.5)
Ig VH Mutation ^**
Unmutated	5 (42%)	7 (58%)	1.0	15.9 (6.5-23.7)	0.66
Mutated	9 (47%)	10 (53%)		15.7 (10.8 - 18.9)
FISH^***
Low/Intermediate Risk	13 (50%)	13 (50%)		15.9 (15.7-23.7)
High Risk	1 (14%)	6 (86%)	0.20^a	10.8 (3.2-18.9)	0.01^a
Del(11q22.3)	1(17%)	5(83%)	0.20^b	7.9 (3.2-13.6)	0.001^b

Zap missing one observation

^**

Mutation missing two observations

^***

FISH low/intermediate risk: del (13q14), trisomy (+) 12, or normal; FISH high risk: del(17p13.1) or del(11q22.3).

p-values for low/intermediate risk vs. high risk ((del(17p13.1) or del(11q22.3))

p-values for low/intermediate risk vs. del(11q22.3) alone