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. Author manuscript; available in PMC: 2010 Aug 10.
Published in final edited form as: J Med Chem. 2007 Aug 16;50(18):4493–4500. doi: 10.1021/jm070569b

Figure 1.

Figure 1

Cell cycle distribution and apoptotic index analyses of HCT-116 cells exposed to doxorubicin or doxazolidine. HCT-116 cells were treated with 400 nM doxorubicin (DOX), doxazolidine (DOXAZ) or vehicle for 3 h and analyzed for (A) cell cycle distribution at 24 post-treatment and (B) apoptosis at 48 h post-treatment. (C) HCT-116 cells were treated with various concentrations of doxorubicin (Inline graphic) and doxazolidine (Inline graphic) for 3 h and analyzed for apoptosis at 48 h post-treatment by annexin V staining.