High Frequency Stimulation (HFS) abolishes network oscillations in the ferret thalamus (A) Spontaneous spindle oscillations in a ferret thalamic slice preparation. Boxed areas indicate segments during which HFS was applied (a,b). Enlargements of segments from the top trace during HFS (duration ∼3s, frequency 100Hz, intensity 300μA, pulse width 100μs) showing absence of spindle wave following HFS. Spontaneous spindle waves return 20-25s following HFS. (B) Schema of thalamic slice preparation demonstrating placement of stimulating and extracellular recording electrodes in the ferret lateral geniculate nucleus (LGN), within ∼100μm of each other.