Table 2. GO categories that are significantly affected in all conditions of EBNA1 expression.

Biological Process	Level	No. of genes	P	Up-regulated	Down-regulated
Cellular component organization and biogenesis
Establishment and/or maintenance of chromatin architecture	5	12	<0.001	HIST1H2BJ, HIST1H2BN, HIST1H2BM, HIST3H2BB, HIST1H2BD, HIST1H2BO, HIST1H2BC, HIST1H2BG, HIST1H2BI, HIST1H2BL	SMARCB1, IGHMBP2
Regulation of cellular process
Regulation of apoptosis	5	4	0.100	NME5, LGALS1, PROC, TRAF1
Molecular function
Binding
Adenyl nucleotide binding	4	6	0.092	NME5, ATP8B2, ATP9A, MAST4	AKT2, IGHMBP2,
Catalytic activity
Nucleoside-triphosphatase activity	7	4	0.093	ATP8B2, ATP9A	FXYD2, IGHMBP2
Cellular component
Non-membrane bound organelle
Chromosome	5	12	<0.001	HIST1H2BJ, HIST1H2BN, HIST1H2BM, HIST3H2BB, HIST1H2BD, HIST1H2BO, HIST1H2BC, HIST1H2BG, HIST1H2BI, HIST1H2BL	SMARCB1, NCAPH2