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. 2010 Aug 10;5(8):e12052. doi: 10.1371/journal.pone.0012052

Table 3. Expansion of selected GO categories during prolonged EBNA1 expression.

GO category GO Level Common Short-term induced Long-term induced Stable
Biological process No. of genes P No. of genes P No. of genes P No. of genes P
Cellular component organization and biogenesis 2 14 0.062 67 <0.001 774 <0.001 622 <0.001
Establishment and/or maintenance of chromatin architecture 5 12 <0.001 24 <0.001 144 <0.001 93 0.001
Regulation of cellular process
Regulation of apoptosis 5 4 0.100 14 0.020 146 0.003 137 <0.001
Molecular function
Binding 2 32 0.023 184 0.001 3017 <0.001 2544 <0.001
Adenyl nucleotide binding 4 6 0.092 26 0.094 438 <0.001 363 <0.001
Catalytic activity
Nucleoside-triphosphatase activity 6 4 0.094 16 0.011 157 0.009 134 0.020
Cellular component
Non-membrane-bound organelle 2 13 0.029 40 0.075 510 <0.001 403 0.019
Chromosome 5 12 <0.001 21 0.001 151 <0.001 110 <0.001