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. 2010 Aug 10;5(8):e12057. doi: 10.1371/journal.pone.0012057

Figure 5. Attenuation of high-fat induced insulin resistance by dietary KAA.

Figure 5

Plasma glucose (A), insulin (B) and calculated indices of HOMA-IR (C) in C57B6 mice 4 weeks before and 8 weeks after feeding with STD, HFD or high-E/N HFD (E/N = 1.8), under 3-hour fasting condition. Using C57B6 mice (n = 6 for each group) fed for 8 weeks with STD, HFD or the high-KAA (high E/N) diet (E/N = 1.8), glucose tolerance tests (GTT) (D), or insulin tolerance tests (ITT) (E) were performed by intraperitoneal glucose or insulin administration (at time = 0) after overnight fasting. *: p<0.05 for all high-fat groups as compared to STD group.