Figure 2. Effect of host background on parasite load and fate.

BALB/c, C57BL/6 or Outbred mice were injected i.p. with 1×10² bloodstream forms of T. vivax and the mean parasitemia recorded individually during infection (A, B, C). Mean mortality (D) is depicted compared to BALB/c mice. Results are given as arithmetic means ± standard deviations of at least three independent experiments. Cumulative mortality was recorded over time for all groups and Kaplan-Meir survival curves plotted for the three mouse strains (D); Comparison between survival curves was performed using Log-rank Mantel-Cox test: * p<0.028, ** p<0.0018, when compared with BALB/c survival.