Table 2.
Estimated haplotype frequencies in NOS1AP
| Haplotype block | Frequency (%) | P values | |||
|---|---|---|---|---|---|
| SCZ | ASD | Control | SCZ vs. control | ASD vs. control | |
| 1 (rs10918776- rs10800405) | |||||
| CT | 0.55 | 0.48 | 0.48 | 0.23 | 0.98 |
| TC | 0.45 | 0.52 | 0.52 | 0.23 | 0.98 |
| 2 (rs3751285 - rs3751285) | |||||
| AG | 0.56 | 0.46 | 0.59 | 0.28 | 0.45 |
| GT | 0.23 | 0.28 | 0.28 | 0.40 | 0.96 |
| AT | 0.11 | 0.17 | 0.13 | 0.74 | 0.33 |
| 3 (rs348624 - rs1964052) | |||||
| CC | 0.89 | 0.85 | 0.91 | 0.50 | 0.07* |
| TT | 0.11 | 0.15 | 0.08 | 0.50 | 0.07* |
| 4 (rs164146 - rs164147) | |||||
| GC | 0.83 | 0.84 | 0.84 | 0.71 | 0.99 |
| CA | 0.18 | 0.16 | 0.16 | 0.71 | 0.99 |
* P = 0.53 when 10000 permutations where simulated. Significant P values (<0.05) are in bold. Abbreviations: ASD: autism spectrum disorders, SCZ: schizophrenia.