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Rag2-/- male mice exhibited a similar response as female Rag2-/- mice. Male wild type or Rag2-/- mice were infected with 2 × 103 or 2 × 105 FFU of influenza A virus PR8 (H1N1) and weight loss and survival was followed for the next 20 days. In addition to mice that were found dead, mice with a weight loss of more than 25% of the starting bodyweight were euthanized and recorded as dead.
