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Immunohistochemical staining of viral NP antigen showed prolonged presence of viral particles in influenza infected Rag2-/- mice. Lung tissue sections from female wild type or Rag2-/- mice infected with 2 × 103 FFU PR8 were prepared on the days p.i. indicated and stained for the presence of viral NP antigen. Three or four mice per group were used, and five slices per animal were evaluated for the NP stain. Scale bar is 200 μm.
