Table 4.
FA SLE > NPSLE | ||||||
---|---|---|---|---|---|---|
Voxels | p-value | Max-t | MNI X | MNI Y | MNI Z | Approximate white matter tract |
155 | 0.003 | 3.286 | -35 | -42 | 22 | Left superior longitudinal fasciculus |
113 | 0.008 | 3.153 | -12 | 6 | 27 | Body of CC |
MD NPSLE > SLE | ||||||
Voxels | p-value | Max-t | MNI X | MNI Y | MNI Z | Approximate white matter tract |
109 | 0.001 | 3.344 | -15 | -15 | 21 | Genu of CC |
73 | 0.006 | 4.107 | -23 | -56 | 22 | Left arm of forceps major |
70 | 0.006 | 3.052 | -23 | 22 | 20 | Left anterior corona radiata |
DTI differences between SLE patients and NPSLE patients. Upper section lists significant regions in which SLE patients had greater fractional anisotropy (FA) than NPSLE patients. Lower panel lists regions in which NPSLE patients had greater mean diffusivity (MD) than SLE patients. Voxels = significant contiguous voxel cluster. Max-t = t statistic of voxel cluster difference between controls and NPSLE. MNI X, Y, Z = Montreal Neurological Institute coordinates of centroid location of significant voxel cluster. CC = corpus callosum.