Table 3.
Pre-BMT Status with Duration Follow-up (median, Range) | Ischemic Stroke after BMT | Cerebral Hemorrhage (ICH) after BMT | Seizure after BMT | MRI Appearance after BMT (Median Duration, Range in Years after BMT) |
---|---|---|---|---|
“Clinical” stroke [n = 29] (7.0, 3.4–12.4 yrs) | N = 1 | N = 1 (SAH) | N = 7 | 27/28 studied had stable or improved MRI; 1 not studied (3.2 years, 0.6–7.3) |
“silent” stroke [n = 10]* (6.7, 3.4–10.6 years) | N = 0 | N = 0 | N = 4 | All 8 studied had stable [4] or improved [4] MRI; 2 not studied (1.7 years, 0.6–4.9) |
Normal (N = 16)† (6.6, 3.1–11.1 years) | N = 0 | N = 0 | N = 5 | All 10 studied had normal MRI; 6 not studied (3.1 years, 0.5–5.2) |
BMT indicates bone marrow transplantation; CNS, central nervous system; ICH, intracranial hemorrhage; MRI, magnetic resonance imaging; SAH, subarachnoid hemorrhage.
Including 4 with no baseline exam.
“Silent stroke” refers to individuals with MRI evidence of cerebrovascular disease without clinical manifestations.