Table 3.

Crude and adjusted odds ratios (ORs) for preterm birth, low birth weight and small-for-gestational-age among offspring of women with a history of cancer compared with offspring of female siblings

Birth outcome	Offspring of survivors N=1309 (%)	Offspring of siblings N= 5916 (%)	Crude OR	95% CI‡	Adjusted OR*	95% CI
Preterm birth (<37wks)	102 (7.8%)	298 (5.0%)	1.59	1.26–2.01	1.46	1.14–1.85
Preterm birth (<34wks)	31 (2.4%)	71 (1.2%)	2.0	1.30–3.06	1.75	1.12–2.72
Low birth weight	80 (6.1%)	221 (3.7%)	1.68	1.29–2.18	1.11†	0.76–1.64
Small-for-gestational-age	37 (2.8%)	162 (2.7%)	1.03	0.72–1.48	0.89	0.61–1.29

^*Adjusted for maternal age, delivery year, child sex, maternal smoking, maternal hypertension, placental problems, use of assisted reproductive technologies, malpresentation and cesarean delivery

^†Additionally adjusted for gestational weeks

^‡95% Confidence interval