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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Semin Cell Dev Biol. 2010 Mar 6;21(7):745–753. doi: 10.1016/j.semcdb.2010.03.001

Figure 5. Processes regulated by Drosophila miR-bantam.

Figure 5

The bantam miRNA controls a wide variety of processes. (A) The most overt defect of bantam mutants are their small size due to failure of cell proliferation, although the relevant target(s) are not known. (B) bantam also prevents apoptosis (cross) by repressing hid, which encodes a pro-apoptotic factor. bantam maintains ovarian germline stem cells (C), and limits the scaling growth of dendrites during larval development (D); the targets mediating these functions are not yet known. (E) Finally, bantam maintains the appropriate length of the circadian clock (represented by an activity trace of animal movements across the day) by regulating clock, which encodes a bHLH-PAS transcription factor.