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. 2010 Apr 12;38(14):4768–4777. doi: 10.1093/nar/gkq232

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Reprocessed dataset displays good agreement with original analysis. (A) Scatter plot displaying the correlation in the numbers of target genes between the reanalysed and original datasets. The data points, one for each knockout experiment, are colour-coded according to the proportion of the original gene list that is recovered. (B) Non-uniform distribution of TF targets for up-regulated (dark grey), down-regulated (light grey) and all differentially expressed genes (black). Data for all TFs are labelled with crosses. Filled circles denote regulators that are down-regulated in their deletion experiment (behaving TFs), while empty circles denote regulators with no significant down-regulation in their deletion.