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. 2010 Apr 14;30(15):5334–5345. doi: 10.1523/JNEUROSCI.5963-09.2010

Figure 1.

Figure 1.

A–T, Preservation of telencephalic regional patterning and features of subpallial differentiation in E15.5 Dlx5/6−/− mutants. The Dlx5/6−/− mutants are exencephalic; a schematic representation of Dlx5/6+/ (S) and Dlx5/6−/− (T) is presented to help the reader orient the regions of the exencephalic telencephalon. Coronal sections from Dlx5/6+/ and Dlx5/6−/− were labeled by in situ hybridization with markers of LGE and MGE progenitor and mantle zones; the Dlx5/6−/− mutants do not show major gene expression defects, although the morphologies of the telencephalic regions are abnormal (A–R). Cx, Cortex; Pd, pallidum (including globus pallidus); St, striatum. Scale bar, 1.5 mm.