Table III.
Count GRS | Continuous GRS | Quartile of Continuous GRS |
|||
---|---|---|---|---|---|
1 | 2 | 3 | 4 | ||
No. Subjects | 2,983 | 630 | 969 | 930 | 454 |
Median GRS (Range) | 6 (2–10) | 5 (2–5) | 6 (6) | 7 (7) | 8 (8–10) |
OR (95% CI)/allele | 1.24 (1.16, 1.33) | 1.0 (-----) | 1.12 (0.91, 1.37) | 1.54 (1.24, 1.90) | 2.07 (1.59, 2.70) |
Adjusted* | 1.21 (1.13, 1.30) | 1.0 (-----) | 1.20 (0.96, 1.49) | 1.49 (1.18, 1.87) | 2.03 (1.53, 2.70) |
Adjusted for hyperlipidemia, hypertension, BMI, diabetes, smoking, family history. (Cases, controls matched for age, sex by design.)