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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Am Heart J. 2010 Aug;160(2):250–256.e3. doi: 10.1016/j.ahj.2010.05.031

Table III.

Associations between Count Genetic Risk Score-5 and Angiographic CAD

Count GRS Continuous GRS Quartile of Continuous GRS
1 2 3 4
No. Subjects 2,983 630 969 930 454
Median GRS (Range) 6 (2–10) 5 (2–5) 6 (6) 7 (7) 8 (8–10)
OR (95% CI)/allele 1.24 (1.16, 1.33) 1.0 (-----) 1.12 (0.91, 1.37) 1.54 (1.24, 1.90) 2.07 (1.59, 2.70)
Adjusted* 1.21 (1.13, 1.30) 1.0 (-----) 1.20 (0.96, 1.49) 1.49 (1.18, 1.87) 2.03 (1.53, 2.70)
*

Adjusted for hyperlipidemia, hypertension, BMI, diabetes, smoking, family history. (Cases, controls matched for age, sex by design.)