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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Am Heart J. 2010 Aug;160(2):250–256.e3. doi: 10.1016/j.ahj.2010.05.031

Table IV.

Multivariable Predictive Model for CAD Using Genetic Variables and Standard Risk Factors

Variable Wald χ2 OR (CI) p Value
Hyperlipidemia 123.51 2.75 (2.30, 3.29) 1.1×10−28
Diabetes 46.12 2.21 (1.76, 2.77) 1.1×10−11
Smoking 39.12 1.98 (1.60, 2.46) 4.0×10−10
Family History 30.01 1.64 (1.37, 1.96) 4.3×10−8
GRS5 / risk allele 28.66 1.21 (1.13, 1.30) 8.7×10−8
Hypertension 2.71 1.16 (0.97, 1.39) 0.10
BMI (per kg/m2) 0.02 1.001 (0.985, 1.018) 0.88*
*

BMI was eliminated from the final model. Effect estimates are for all variables considered simultaneously.