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. 2010 Jul 6;107(29):13159–13164. doi: 10.1073/pnas.1003432107

Fig. 2.

Fig. 2.

Quantification of monoamines in striatal tissue samples using HPLC. Two groups of animals were analyzed to determine the concentrations of DA and its metabolites under baseline conditions or following L-DOPA treatment on the uninjected control side (A) and injected side (B). In addition the turnover rate for DA (C) and 5-HT (D) were calculated. Data are analyzed by two-way factorial ANOVA [B, treatment vs. group effect F(7,37) = 13.479, P < 0.0001; C, group vs. side effect F(7,41) = 5.194, P < 0.0001], followed by Tukey's HSD post hoc test. Error bars represent ± SEM. *Different from intact and shTHscr control groups within the same condition (A and B) or side (C and D). +Different from baseline condition (B) or intact side (C).