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Impaired osteoclast development in PI3Kγ-deficient bones. Histomorphometric analysis of TRAP-stained tibiae from PI3Kγ-null and WT mice (4 mo old, male). (A) Representative images of TRAP-stained tibia sections. (B) Osteoclast surface per bone surface (Oc.S/BS). (C) Number of osteoclasts per bone perimeter (N.Oc/B.Pm.). *P < 0.05 vs. WT. Data are shown as mean ± SEM, n = 12.
