Table 1. Detail of patient groups.
Training SELDI | Validation-1 SELDI | Validation-2 ELISA | |
---|---|---|---|
n | n | n | |
Pancreatic ductal adenocarcinoma | 38 | 40 | 33 |
Male | 20 | 23 | 15 |
Female | 18 | 17 | 18 |
Stage I | 7 | — | 1 |
Stage IIa | 5 | 4 | 7 |
Stage IIb | 8 | 36 | 14 |
Stage IV | 18 | — | 11 |
Disease control | 54 | 21 | 28 |
Male | 28 | 18 | 16 |
Female | 26 | 3 | 12 |
Cholelithiasis | 17 | 2 | |
Choledocholithiasis | 6 | ||
Intraductal papillary mucinous neoplasm | 6 | — | 1 |
Carotid artery stenosis | — | 6 | |
Mucinous cystadenoma | 5 | — | 2 |
Neuroendocrine (islet cell) tumour | 5 | — | 7 (4) |
Gallstone pancreatitis | 4 | — | 2 |
Chronic pancreatitis | 4 | 1 | 2 |
Benign stricture | 2 | ||
Hernia | 3 | 2 | |
Acute cholecystitis | — | 3 | |
Othera | 10 | 7 | 3 |
Healthy volunteer | 68 | 19 | 18 |
Male | 28 | 12 | 9 |
Female | 40 | 7 | 9 |
Abbreviation: SELDI=surface-enhanced laser desorption and ionisation.
The number in brackets indicates malignant islet cell tumours.
Other includes: Training Set – villous adenoma (n=2), serous cystadenoma (n=2), pancreatic pseudocyst (n=2), solid pseudopapillary tumour (n=1), Caroli's disease (n=1), gastro-oesophageal reflux (n=1) and ruptured appendix (n=1); Validation-1 Set – leg ischaemia (n=2), rectal bleeding (n=2), diaphragmatic hernia (n=1), phlebitis (n=1) and haematological disorder (n=1); and Validation-2 Set – solitary fibrous tumour, granulomata, intrapancreatic pseudocyst.