Table 2. Mean and s.e.m. of age and biochemical indices for patient groups.
Pancreatic cancer
|
Disease controls
|
P-value | ||||
---|---|---|---|---|---|---|
Values | Set | Mean | s.e.m. or range | Mean | s.e.m. or range | PC vs DC |
Age (years) | Training | 70.9 | (28–80) | 62.7 | (32–81) | NS |
Validation-2 | 69.7 | (32–81) | 57.1 | (18–89) | NS | |
Urea (mmol l–1) | Training | 5.9 | 0.5 | 5.1 | 0.4 | NS |
Validation-2 | 5.8 | 0.4 | 5.6 | 0.6 | NS | |
Bilirubin (μmol l–1) | Training | 144 | 33 | 18 | 3 | 0.001 |
Validation-2 | 88 | 20 | 49 | 21 | 0.01 | |
Albumin (g l–1) | Training | 35.1 | 1.2 | 41.1 | 0.8 | 0.001 |
Validation-2 | 35.5 | 1.1 | 39.4 | 1.1 | 0.017 | |
AST (IU l–1)a | Training | 111 | 19 | 50 | 10 | 0.001 |
Validation-2 | 98 | 19 | 53 | 9 | 0.049 | |
ALT (IU l–1)a | Training | 154 | 28 | 76 | 21 | 0.005 |
Validation-2 | 143 | 32 | 94 | 26 | NS | |
ALP (IU l–1)a | Training | 362 | 60 | 101 | 14 | 0.001 |
Validation-2 | 316 | 45 | 172 | 23 | 0.007 | |
GGT (IU l–1)a | Training | 489 | 102 | 130 | 43 | 0.001 |
Validation-2 | 561 | 111 | 208 | 49 | 0.006 | |
CA19-9 (U l–1)a | Training | 1594 | 960 | 32 | 7 | 0.001 |
Validation-2 | 1466 | 922 | 31 | 9 | 0.001 |
Abbreviations: ALP= alkaline phosphatase; AST= glutamic-oxaloacetic transaminase; ALT= glutamic-pyruvic transaminase; CA19-9= carbohydrate antibody 19-9; DC= disease control; GGT= γ-glutamyltransferase; NS= not significant; PC= pancreatic cancer.
Results are for serum values.
P-value indicates Mann–Whitney U-test result.