Table 3. Treatment-related adverse events.
| Toxicity | Grade | No. of patients (all cycles) |
|---|---|---|
| Figitumumab related | ||
| Elevated ALT | 1/2 | 5 |
| 3/4 | 0 | |
| Elevated GGT | 1/2 | 3 |
| 3/4 | 0 | |
| Fatigue | 1/2 | 2 |
| 3/4 | 1 | |
| Hyperglycaemia | 1/2 | 1 |
| 3/4 | 1 | |
| Muscle spasm | 1/2 | 3 |
| 3/4 | 0 | |
| Nausea | 1/2 | 3 |
| 3/4 | 0 | |
| Docetaxel related | ||
| Alopaecia | 1/2 | 3 |
| 3/4 | 0 | |
| Anorexia | 1/2 | 6 |
| 3/4 | 0 | |
| Cellulitis | 1/2 | 0 |
| 3/4 | 1 | |
| Diarrhoea | 1/2 | 8 |
| 3/4 | 5 | |
| Deep-vein thrombosis | 1/2 | 1 |
| 3/4 | 1 | |
| Fatigue | 1/2 | 16 |
| 3/4 | 9 | |
| Febrile neutropaeniaa | 1/2 | 0 |
| 3/4 | 11 | |
| Leukopaenia | 1/2 | 3 |
| 3/4 | 7 | |
| Lymphopaenia | 1/2 | 2 |
| 3/4 | 1 | |
| Mucositis | 1/2 | 4 |
| 3/4 | 0 | |
| Nausea | 1/2 | 3 |
| 3/4 | 0 | |
| Neutropaenia | 1/2 | 4 |
| 3/4 | 28 | |
| Pain | 1/2 | 3 |
| 3/4 | 1 |
Abbreviations: ALT=alanine aminotransferase; GGT=γ-glutamyl transferase.
a
Includes neutropenic sepsis.