Figure 1.

A: Comparison of the C1 chain and the 80’s loop of the C2 chain of the T_{high_apo} with corresponding portions of the T_{low_apo} structure. B: Comparison of the C1 chain and the 80’s loop of the C2 chain of the T_{high_apo} with corresponding portions of the R_{low_pala} structure. The width of the tube is proportional to the RMS deviation of the a-carbon atom positions. Also shown is the 80’s loop from the adjacent catalytic chain that contributes residues to the active site (80’s Loop*). C: Stereoview of a superposition of the a-carbon atoms of the T_{high_apo} (blue), T_{low_apo} (gray), and the R_{low_pala} (green) structures. Parts A and B were prepared using CHIMERA,⁴³ whereas Part C was prepared using PyMol.⁴⁴