Table 4. Comparison of Mean and SD for individual ACR tests, Cognitive Impairment Index and Memory Impairment Index Across groups.
T-scores for Individual ACR Tests (see legend below) | nonNPSLE N=43 | Controls N=27 | p-value from Student t-test | ||
---|---|---|---|---|---|
Mean | Std Dev | Mean | Std Dev | ||
Digit Symbol | 48.44 | 10.65 | 52.33 | 7.88 | 0.106 |
Letter-Number Sequencing | 51.47 | 10.59 | 56.15 | 9.62 | 0.067 |
Stroop Color-Word | 50.33 | 8.67 | 53.07 | 9.22 | 0.212 |
Trail Making Part B | 52.07 | 10.41 | 51.85 | 9.71 | 0.930 |
Letter fluency | 46.21 | 10.34 | 44.44 | 10.99 | 0.500 |
Category fluency | 49.95 | 9.79 | 49.22 | 7.74 | 0.743 |
Verbal learning | 48.49 | 11.26 | 53.33 | 12.51 | 0.098 |
Verbal recall | 45.35 | 11.41 | 51.67 | 10.74 | *0.022 |
Nonverbal recall | 36.42 | 12.33 | 41.19 | 11.31 | 0.109 |
Nonverbal learning | 38.67 | 11.70 | 42.93 | 12.03 | 0.148 |
Tapping-dominant hand | 50.98 | 11.78 | 50.56 | 9.51 | *0.709 |
Tapping-non-dominant hand | 49.21 | 9.29 | 51.67 | 10.03 | 0.300 |
Impairment Indices | |||||
Cognitive Impairment Index (range 0-12) | 2.63 | 2.21 | 2.04 | 1.63 | 0.236 |
Memory Impairment Index (range 0-4) | 1.56 | 1.35 | 1.15 | 1.26 | 0.209 |
p-value for Verbal recall and Tapping-dominant hand from Wilcoxon Rank Sums test for non-normally distributed data. For Verbal recall, the median (inter-quartile range) for nonNPSLE was 45 (15) and 55 (15) for controls. For Tapping-dominant hand, the median (interquartile range) for SLE was 50 (19) for SLE and 50 (7) for controls.
Digit Symbol=Wechsler Adult Intelligence Scale-Revised Digit Symbol Test, total score; Letter-Number Sequencing=Wechsler Adult Intelligence Scale-III Letter Number Sequencing Test, total score; Stroop Color Word=Stroop Color-Word Test, color-word score; Trail Making Part B=Trail Making Test-Part B, total completion time; Letter fluency=Controlled Oral Word Association Test, letters F, A, and S; Category fluency=Animal Naming Test, total score; Verbal recall=California Verbal Learning Test-II, short-delayed recall; Verbal learning=California Verbal Learning Test-II, learning trials 1-5; Nonverbal recall=Rey-Osterrieth delayed recall; Nonverbal learning= Rey-Osterrieth immediate recall; Tapping-dominant hand=Finger Tapping Test-dominant hand; Tapping-non-dominant hand =Finger Tapping Test-non-dominant hand