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Expression of MUC4 in malignant melanoma. Malignant melanoma without prominent melanin granules was uniformly negative for MUC4. Representative sections: (A,B) H&E; (E,F) MUC4 stained. Focal, weak MUC4 expression was noted in those melanomas where the tumour cells expressed melanin granules. Representative sections: (C,D) H&E to demonstrate melanin granules; (G,H) MUC4 stained. (A,C,E,G) Magnification ×100; (B,D,F,H) magnification ×200; insets, low magnification (×40).
