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. Author manuscript; available in PMC: 2011 Aug 15.
Published in final edited form as: Dev Biol. 2010 Jun 20;344(2):1110–1118. doi: 10.1016/j.ydbio.2010.06.020

Figure 2.

Figure 2

Linear cascade with OR logic versus feedforward structure. A. Schematic diagram of linear cascade where both genes B and C have multiple inputs and the cis-regulatory modules execute OR logic on these inputs. B. Schematic diagram of feedforward structure where transcription factor A activates gene B and together they activate gene C in AND logic. C. The protein level of gene B in WT condition (red) and in A MASO treatment (orange). D. The mRNA level of the downstream gene, C, for linear cascade at WT condition (blue) and at A MASO treatment (green). E. The mRNA level of the downstream gene, C, for feedforward structure at WT and A MASO treatment. Same color scheme as in D. Kinetic parameters for all simulations are the same as in Fig. 1.