Table 2.
Author | Eligibility criteria | Criteria for intervention | Median age | Median follow-up | DSS |
---|---|---|---|---|---|
Dall-Era, et al13 | T1–1, GS ≤ 6, PSA <10 ng/mL % positive cores <33% | GS ≥ 7, increase PSA or tumor volume | 63 yrs | 43 mos | 100% |
Klotz14 | T1c–T2a, GS ≤ 6, PSA ≤ 10 ng/mL | PSADT ≤ 3yrs, PSA > 10 ng/mL, PSAV 2 ng/mL/yr | 70 yrs | 72 mos | 99% |
Abbreviations: PSA, prostate specific antigen; GS, gleason score; PSADT, PSA doubling time; PSAV, PSA velocity; DSS, disease specific survival.