The amino acid sequences of OA/TAMac are aligned with homologous invertebrate species. Heavy lines and Roman numbers above the sequence indicate transmembrane regions 1–7. Black boxes with white letters represent areas of identical regions, dark gray boxes with black letters represent conserved regions, and light gray boxes with black letters represent blocks of similar regions. Accession numbers are: cabbage moth Mamestra brasicae, AAK14402; tobacco budworm Heliothis virescens, Q25188; silkworm Bombyx mori, NP_001037504 and BAD11157; fly Drosophila melanogaster, AAA28731 and NP_524419; migratory locust LocusTYR Migratoria, Q25321 and Q25322; freshwater prawn Macrobrachium rosenbergii, EU233816. Abbreviations: octopamine receptor (OctR); tyramine receptor (TyrR); tyramine receptor 1 (TyrR1); tyramine receptor 2 (TyrR2); tyramine/octopamine receptor (Tyr/Oct).