Skip to main content
. 2010 Jul 29;7:175. doi: 10.1186/1743-422X-7-175

Figure 6.

Figure 6

Adenovirus co-replication enhancement of immune modulators CD40L and IL-2 expressed from CMV promoter cassette. Melanoma M000301 or colon SW480 cells were infected with AdCMV-CD40L (A, B), or AdCMV-IL-2 (C), at an MOI of 1.1, and were combined with 3-fold increasing amounts of RC wtAd5 and AdΔEP-TETP, or the replication-defective E1-deleted AdCMV-lacZ. The resulting ratios of RC/transgene vector are indicated. CD40L and IL-2 transgene expression analyses were performed two days p.i. by flow cytometry and ELISA, respectively. Asterisks indicate the level of significance (*P < 0.05; **P < 0.005; for comparison with corresponding wtAd5/AdCMV-CD40L values).