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Immunofluorescence staining of HAECs with CD31 in various groups. The Incubation of HAECs with high glucose (30 mM) for 48 h resulted in a fibroblast-like phenotype (B). Treatment with irbesartan could significantly prevent the morphological changes (C). NG: normal glucose. HG: high glucose. HI+Irb: high glucose + Irbesartan.
