Figure 5. Treatment with 20µM Cu₁₀MT-2A or CaMeMT-2A had no protective effect against 40µM Aβ_1–40 (in the presence of 40µM CuCl₂ and 300µM ascorbate) (A).

Treatment of cortical neurons with 10µM or 100µM H₂O₂ for two hours resulted in substantial neuronal death, which was not prevented by co-treatment with 20µM Zn₇MT-2A (B). Error bars represent standard error of the mean calculated from at least three experimental replicates. In panel A, * - p<0.05 compared to untreated cells (One-Way ANOVA). In panel B, Two-Way ANOVA analysis was performed, and * - p<0.05 compared to untreated cells, # - p<0.05 between treatments.