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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: J Hypertens. 2010 Sep;28(9):1913–1919. doi: 10.1097/HJH.0b013e32833c2289

Fig. 4.

Fig. 4

Effects of PI3K blockade on the lumbar sympathetic nerve activity (SNA) responses to ICV insulin in lean controls (A) and agouti obese mice (B). PI3K inhibitor LY294002 (0.01 and 0.1 μg) or vehicle were given ICV, 10 min before ICV insulin or vehicle. Data represent means±SEM; n=6–9 mice per group.

* P<0.05 vs. vehicle; † P<0.05 vs. vehicle-insulin group.