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. 2010 Jun 10;13(4):508–516. doi: 10.1016/j.mib.2010.05.009

Figure 1.

Figure 1

Viral antagonism with the IFN circuit. A check symbol is displayed at various steps of the IFN cascade (X-axis) that are impaired by a particular virus (Y-axis). The plot is organized by viral genome type. Double symbols indicate inhibition of IFN induction or signaling at yet unknown step of the pathway. Black symbols indicate proof for viral antagonism of the indicated step in the pathway by recombinant viruses lacking the IFN antagonist. Grey symbols indicate proof by over expression and/or wild-type virus infection.